Osteogenesis Imperfecta Foundation

Voluntary Health Agency Member

Address: 
804 West Diamond Avenue
Suite 210
Gaithersburg, MD 20878
Phone: 
301-947-0083
Fax: 
301-947-0456

The Osteogenesis Imperfecta Foundation, Inc. (OI Foundation) is the only voluntary national health organization dedicated to helping people cope with the problems associated with osteogenesis imperfecta. The OI Foundation began in 1970 when a small group of parents from around the nation met in Chicago to discuss OI and its problems. At that time, they banded together to stimulate public and professional interest, support families and encourage research. Today, the Foundation's mission is to improve the quality of life for individuals affected by OI through research to find treatments and a cure, education, awareness, and mutual support.

Osteogenesis imperfecta (OI) is a genetic disorder characterized by bones that break easily, often from little or no apparent cause. There are at least four recognized forms of the disorder, representing extreme variation in severity from one individual to another. OI is caused by a genetic defect that affects the body's production of collagen. Collagen is the major protein of the body's connective tissue and can be likened to the framework around which a building is constructed. In OI, a person has either less collagen than normal, or a poorer quality of collagen than normal--leading to weak bones that fracture easily. A person may have just a few or as many as several hundred fractures in a lifetime.

This organization has completed the National Health Council’s Standards of Excellence Certification Program and meets the highest standards of accountability, ethical practice, organizational effectiveness, and good public stewardship.